Family systems (especially caregivers) play a critical role for young people in reducing risks and promoting strengths that lead to healthy development. Extended family units, including caregivers, are critical components of a microsystem that are often overlooked by child welfare and juvenile justice systems. More specifically, when child maltreatment, drug treatment, incarceration, human trafficking, divorce, and/or separation disrupts the family system, the social service systems called on to help in these difficult times are less likely to consider the role of extended family units as they design interventions for the impacted children. Given that families play a critical role in prevention and intervention outcomes for their children, my research evaluates challenges and barriers experienced by families and how these experiences impact the effectiveness of interventions for their children.